PLATELET-RICH PLASMA (PRP) AND TRANEXAMIC ACID (TXA) APPLIED IN TOTAL KNEE ARTHROPLASTY

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Platelet-rich plasma (PRP) applied during total knee arthroplasty☆

OBJECTIVE To evaluate the efficacy of platelet-rich plasma regarding healing, pain and hemostasis after total knee arthroplasty, by means of a blinded randomized controlled and blinded clinical study. METHODS Forty patients who were going to undergo implantation of a total knee prosthesis were selected and randomized. In 20 of these patients, platelet-rich plasma was applied before the joint ...

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Tranexamic Acid and Total Knee Arthroplasty

Total knee arthroplasty (TKA) is one of the most commonly performed elective orthopaedic procedures in the United States [1]. By 2030, the number is estimated to grow by 673% to 3.48 million TKAs performed a year [1]. TKA provides significant pain relief and improvement in quality of life [2]. However TKA surgery is not without complications. Of note is the risk of bleeding and requirement for ...

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Platelet-rich plasma (PRP) for knee disorders

Platelet-rich plasma (PRP) is an autologous blood product with platelet concentrations above baseline values. The process involves the extraction of blood from the patient which is then centrifuged to obtain a concentrated suspension of platelets by plasmapheresis. It then undergoes a two-stage centrifugation process to separate the solid and liquid components of the anticoagulated blood. PRP o...

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Intraarticular Injections of Platelet-rich Plasma (PRP)in the Management of Knee Osteoarthritis

  The clinical use of PRP therapy in the practical setting of orthopaedic fields is increasing partly because of the accessibility of devices that are used in outpatient preparation and delivery. Another reason is the strong advertisement of PRP procedures as the ultimate treatment and novel technology for knee problems by a few orthopaedic surgeons based on claims of abundant scientific eviden...

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  Despite improvements in surgical and anesthetic techniques, total joint arthroplasty (TJA) is still associated with substantial blood loss and postoperative anemia (1). A considerable portion of patients with postoperative anemia require blood transfusion, which has been shown to negatively affect the outcome of TJA and predisposes patients to development of surgical site infection and peripr...

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ژورنال

عنوان ژورنال: Acta Ortopédica Brasileira

سال: 2019

ISSN: 1809-4406,1413-7852

DOI: 10.1590/1413-785220192705214417